HCC shows nodular enhancement in arterial phase, washout in portal venous phase and hypointensity in hepatobiliary phase as malignant cells of HCC cannot retain hepatobiliary contrast agents. But what about the nodules that are hypointense in hepatobiliary phase but show no arterial phase hyperenhancement? How many of them are HCCs? Is there a way we can identify progressed HCC among such nodules?
Dr Argha Chatterjee, Tata Medical Center, Kolkata, discusses in detail an exciting Radiology paper which throws light on this issue in the Cafe Roentgen journal watch video.